Euroa is a 1 hr 45 min drive from Melbourne via the M31 Hume Freeway. Take the Euroa exit off the Hume Freeway approximately 160 North-East of Melbourne.
Sydney is a 7 hour drive via the M31 Hume Freeway to Euroa (Route C312). However don't forget to allow for breaks.
Regional road route C3666 links Euroa from the North-West from Shepparton (40 min) and Merton (20 min) to the South where this road links to the Maroondah Highway.